Appalachia Region

Appalachian American Genealogy a gateway to genealogy resources for 83 counties in Tennessee, Georgia, North Carolina and South Carolina known as the “Tri-State Area” plus the Northwestern area of South Carolina because it was significant in ancestors’ migration patterns into the southern Appalachian area
Archives of Appalachia – East Tennessee State University
Southern Appalachian Archives – Berea College, Kentucky
Southern Appalachian Archives – at Ramsey Center, Mars Hill University

Also see individual states in Appalachia:

Alabama
Georgia
Kentucky
North Carolina
Tennessee
Virginia